What are Polyneucleotides?

Polynucleotides are a newly emerging trend in anti-ageing injections that stimulate tissue repair and encourage restoration and regeneration of the skin from within.

With over 90 clinical trials and a proven track record in tissue and cartilage regenerative medicine, the evidence for the power of Polynucleotides is undisputed in both the medical and aesthetic fields.

Polynucleotides are long chains of nucleotides that make up DNA and RNA molecules. They are derived from fragments of fish DNA (which resemble human DNA), which initiate your body’s natural fibroblast production, resulting in increased collagen (47% in 23 days) and a thicker, healthier epidermis (52% in 23 days).

They can be used in a wide range of applications as a rejuvenating treatment for older skin and as a preventative treatment for younger skin. The list of applications

What are the benefits of polyneucleotides?

  • They stimulate the production of collagen and elastin, which helps to improve skin elasticity and firmness, enhancing the results of other treatments, as well as reducing the appearance of wrinkles and sagging skin.
  • They reduce inflammation, restoring volume and hydration to the skin
  • They Help to protect the skin from damage caused by the sun
  • Little downtime compared to other injectables
What do Polyneucleotides treat?

Polynucleotides are being used to reverse the ageing of tissues and repair scarring by tackling the concern from the source, in contrast to the traditional treatments, for example with fillers, which focuses on treating symptoms. Some of the applications of polynucleotides include:

  • Holistic skin revitalisation to combat general signs of ageing
  • Treatment of dark under eye circles as an alternative to tear trough
  • Acne
  • Atrophic scarring
  • Rosacea
  • Alopecia/hair loss
  • Hyperpigmentation
  • Stretch marks
  • Deep lines & wrinkles
  • Rehydration for dull skin at any age
  • Preventative treatment for young skin

In addition to their success rate with these applications, polynucleotides work well alongside other treatments, enhancing their effects, such as by boosting the longevity of anti-wrinkle injections.

Are there any side effects?

Side effects of polynucleotides are generally minimal, with the main potential side effects relating to the site of the injection, where patients may experience redness, swelling and bruising which should settle after one to two days. More serious side effects, such as allergic reactions, are extremely rare. As with all treatments, it’s important to carry out a thorough pre-treatment consultation to assess the patient’s suitability.

How quickly will I see results after polynucleotides treatment?

Unlike with dermal fillers, which have an instant effect, patients won’t notice the full benefits with polynucleotides immediately. This is because the action is at the cellular level and it takes time to become apparent, but patients may see some improvement after two to three weeks.

How long do polynucleotides treatment results last? 

Results last around six to nine months on average, depending on the patient’s lifestyle and rate of ageing.


What happens during a polynucleotides treatment?

Before the treatment a numbing cream can be applied to the patient, especially if there are multiple injections involved. Depending on the area of treatment, the polynucleotides can be injected via two methods. The first are very tiny needles, alternatively, a blunt-ended cannula may be used to spread the product evenly. The process usually takes about 20-30 minutes.